Biomarkers on the Brain: From Sequencing to Functional Imaging


LIVE Symposium

Monday, December 13, 2021
1:00 – 4:00 PM Eastern Time

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There is an urgent need for quantitative biomarkers for neurological and psychiatric disorders to assess disease risk, facilitate diagnoses, and measure drug treatment efficacy. Due to the selective permeability of the blood-brain barrier, there are only trace amounts of brain-derived proteins in the plasma and cerebrospinal fluid, which makes it challenging to develop convenient biomarker testing for brain disorders. Researchers look beyond the traditional protein assays and combine transcriptomics and functional imaging approaches to revolutionize brain disorder diagnostics.

In this virtual symposium, an expert panel will discuss how advances in single-cell sequencing, fluid-based RNA detection, and functional imaging accelerate biomarker discovery to better understand the brain in health and disease.

Symposium program

1:10 PM – Identifying Disease-Relevant Biomarkers for Spinal Muscular Atrophy

Allison D. Ebert, PhD

1:40 PM – A Lymphocyte-Microglia-Astrocyte Axis in Chronic Active Multiple Sclerosis

Martina Absinta, PhD

2:10 PM – EEG Biomarkers of Fine-Scale Brain Connectivity Changes in Mental Disorders

Etay Hay, PhD

2:40 PM – Immune Biomarkers in Bipolar Disorder and Their Genetic Basis

Sarah Bergen, PhD

3:10 – 4:00 PM – Open panel Q&A session
Sejal Davla from The Scientist’s Creative Services Team will be joined by the entire panel in an open question and answer session where presenters will address questions posed by the audience.

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Meet the speakers

Allison D. Ebert, PhD
Associate Professor
Department of Cell Biology, Neurobiology, and Anatomy
Director, Neuroscience Doctoral Program
Medical College of Wisconsin, Milwaukee

Martina Absinta, PhD
Junior Faculty
Vita-Salute San Raffaele University
Milan, Italy

Etay Hay, PhD
Independent Scientist
Krembil Centre for Neuroinformatics
Centre for Addiction and Mental Health
Assistant Professor
Departments of Physiology and Psychiatry
                                 University of Toronto

Sarah Bergen, PhD
Associate Professor
Department of Medical Epidemiology and Biostatistics
Karolinska Institute, Stockholm, Sweden

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